Slicing off a piece of aficamten for Bayer

Week 47 Deals (2024)

Deal of the Week: Cytokinetics & Bayer Licensing Collaboration for Aficamten in Japan [GlobeNewswire] 

Bayer secures exclusive rights to commercialize aficamten in Japan, expanding its cardiovascular portfolio

  • Structure: Exclusive licensing agreement 

  • Date Announced: November 19, 2024 

  • Total Deal Value: Not disclosed 

  • Phase: Phase 3 

  • Therapeutic Focus: Cardiomyopathy (heart failure) 

  • Strategic Impact: This deal strengthens Bayer’s cardiovascular pipeline and positions aficamten for success in the Japanese market. 

Notable Deals

Steritas & Argenx Collaboration on Steroid-Sparing Therapeutics [BusinessWire]

Argenx and Steritas team up to develop steroid-sparing options for autoimmune diseases

  • Structure: Research collaboration agreement 

  • Date Announced: November 19, 2024 

  • Total Deal Value: Not disclosed 

  • Phase: Preclinical 

  • Therapeutic Focus: Autoimmune diseases 

Flagship Pioneering & Pfizer Expand Strategic Partnership [PRNewswire]

Flagship companies Ampersand Biomedicines and Montai Therapeutics join Pfizer’s innovation ecosystem

  • Structure: Multi-company partnership agreements under Pfizer’s strategic collaboration with Flagship Pioneering 

  • Date Announced: November 20, 2024 

  • Total Deal Value: Not disclosed 

  • Phase: Discovery 

  • Therapeutic Focus: Precision medicine and novel therapeutic modalities 

23andMe & Mirador Therapeutics Research Collaboration [GlobeNewswire]

Advancing precision medicines for immunology and inflammation through strategic research collaboration 

  • Structure: Strategic research collaboration agreement 

  • Date Announced: November 20, 2024 

  • Total Deal Value: Not disclosed 

  • Phase: Discovery 

  • Therapeutic Focus: Immunology and inflammation 

Kura Oncology & Kyowa Kirin Global Collaboration on Ziftomenib [GlobeNewswire]

Developing and commercializing Ziftomenib for acute leukemias globally 

  • Structure: Global strategic collaboration agreement 

  • Date Announced: November 20, 2024 

  • Total Deal Value: Not disclosed (likely includes milestone payments and royalties) 

  • Phase: Phase 2/3 

  • Therapeutic Focus: Acute myeloid leukemia 

Zai Lab & Pfizer Strategic Collaboration on XACDURO® [BusinessWire]

Commercialization partnership for novel antibacterial drug in Asia-Pacific markets

  • Structure: Strategic collaboration agreement 

  • Date Announced: November 21, 2024

  • Total Deal Value: Not disclosed

  • Phase: Marketed 

  • Therapeutic Focus: Antibacterial therapy 

 Vilya & University of Washington Licensing Agreement [GlobeNewswire]

Exclusive license for RFdiffusion-based generative model to design macrocyclic peptides

  • Structure: Exclusive licensing agreement for computational drug design technology 

  • Date Announced: November 21, 2024 

  • Total Deal Value: Not disclosed 

  • Phase: Discovery