Strategic acquisitions and collaborations dominate the week

Week 41 Deals (2024)

Deal of the Week: Recordati & Sanofi (Source)

Recordati strengthens rare diseases portfolio with global rights to Enjaymo 

  • Structure: Acquisition of global rights to Enjaymo (sutimlimab), a treatment for cold agglutinin disease (CAD)

  • Date Announced: October 4, 2024

  • Total Deal Value: €1.2 billion

  • Upfront Cash: €800 million

  • Milestones: €400 million in potential regulatory and sales-based milestones

  • Royalties: Undisclosed

  • Other Terms: Recordati will take over all commercial and manufacturing responsibilities for Enjaymo globally

Notable Deals

Bayer & MOMA Therapeutics (Source)

Bayer partners with MOMA Therapeutics on oncology treatments

  • Structure: Collaboration and license agreement focused on developing precision oncology therapies targeting molecular machines

  • Date Announced: October 8, 2024

  • Total Deal Value: $1 billion

  • Upfront Cash: $150 million

  • Milestones: $850 million in development, regulatory, and commercial milestones

  • Royalties: Tiered royalties on future sales

Innovent & ASK Pharm (Source)

Innovent and ASK Pharm collaborate on third-generation EGFR TKI for lung cancer

  • Structure: Strategic collaboration for the development and commercialization of Limertinib, a third-generation EGFR TKI for lung cancer treatment in China

  • Date Announced: October 7, 2024

  • Total Deal Value: $700 million

  • Upfront Cash: $100 million

  • Milestones: $600 million in potential milestones based on development and sales achievements

Astellas & AviadoBio (Source)

Astellas secures exclusive option for gene therapy AVB-101 targeting frontotemporal dementia

  • Structure: Exclusive option and license agreement for AVB-101, a gene therapy targeting frontotemporal dementia and other neurological indications

  • Date Announced: October 8, 2024

  • Total Deal Value: $500 million

  • Upfront Cash: $50 million

  • Milestones: $450 million in development and commercial milestones

Boehringer Ingelheim & Circle Pharma (Source)

Boehringer Ingelheim teams up with Circle Pharma to develop novel precision cancer therapies

  • Structure: Research collaboration to develop macrocycle-based precision therapies for cancer treatment

  • Date Announced: October 9, 2024

  • Key Terms: Boehringer Ingelheim will leverage Circle Pharma's macrocycle platform to identify novel compounds targeting specific cancer pathways. Financial terms were not disclosed.

Qinotto & Lilly (Source)

Qinotto and Lilly enter research collaboration for novel pain therapeutics

  • Structure: Research collaboration and license agreement focused on discovering novel pain therapeutics using Qinotto's platform

  • Date Announced: October 8, 2024

  • Key Terms: Lilly will gain exclusive rights to develop and commercialize any resulting therapies. Financial terms were not disclosed.

Tonix Pharmaceuticals & X-Chem (Source)

Tonix Pharmaceuticals partners with X-Chem to develop broad-spectrum antivirals using AI

  • Structure: AI-driven collaboration focused on discovering broad-spectrum antiviral treatments

  • Date Announced: October 8, 2024

  • Key Terms: X-Chem will apply its AI technology to identify potential antiviral candidates. Financial terms were not disclosed.